As an intramuscular premedication for patients with physical status ASA I-IV who are to undergo surgical procedures.
For this indication, competent medicine agencies globally authorize below treatments:
Intramuscular
0.07 - 0.1 mg per kg of body weight
From 0.07 To 0.1 mg per kg of body weight once every day
A single intramuscular injection of 0.07-0.1mg/kg body-weight, administered 30-60 minutes pre-operatively, has been shown to be adequate in most cases. The usual dose is about 5mg.
Atropine or hyoscine hydrobromide may be given concomitantly, bearing in mind that hyoscine hydrobromide will enhance and prolong the sedative and amnesic effects of midazolam.
Midazolam injection can be combined with atropine or hyoscine hydrobromide in the same syringe to be given as a single intramuscular injection.