Lower respiratory tract disease (LRTD) caused by respiratory syncytial virus

Active Ingredient: RSV glycoprotein F antigen

Indication for RSV glycoprotein F antigen

Population group: only adults (18 years old or older)
Therapeutic intent: Preventive action

Adjuvanted RSVPreF3 vaccine is indicated for active immunisation for the prevention of lower respiratory tract disease (LRTD) caused by respiratory syncytial virus in adults 60 years of age and older.

The use of this vaccine should be in accordance with official recommendations.

For this indication, competent medicine agencies globally authorize below treatments:

0.5 mL once

For:

Dosage regimens

Intramuscular, 0.5 milliliters rSV glycoprotein F antigen, one dose.

Detailed description

Adjuvanted RSVPreF3 vaccine is administered as a single dose of 0.5 mL.

The need for revaccination with a subsequent dose has not been established.

Dosage considerations

For intramuscular injection only, preferably in the deltoid muscle.

Active ingredient

RSV glycoprotein F antigen

RSV glycoprotein F antigen is designed to enhance antigen-specific cellular immune response and neutralizing antibodies response in individuals with pre-existing immunity against RSV. The adjuvant AS01E facilitates the recruitment and activation of antigen presenting cells carrying vaccine-derived antigens in the draining lymph node, which in turn leads to the generation of RSVPreF3-specific CD4+ T cells.

Read more about RSV glycoprotein F antigen

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