Diabetes mellitus type 2

Active Ingredient: Luseogliflozin

Indication for Luseogliflozin

Population group: only adults (18 years old or older)
Therapeutic intent: Curative procedure

Luseogliflozin is indicated in the treatment of type 2 diabetes mellitus to improve glycemic control in adults as:

Monotherapy

When diet and exercise alone do not provide adequate glycemic control in patients for whom use of metformin is considered inappropriate due to intolerance.

Add-on combination therapy

In combination with glucose-lowering medicinal products including insulin preparations in adult patients with type 2 diabetes mellitus to improve glycemic control when diet and exercise plus monotherapy does not provide adequate glycemic control.

For this indication, competent medicine agencies globally authorize below treatments:

2.5-5 mg once daily

For:

Dosage regimens

Oral, 2.5 milligrams luseogliflozin, to breakfast. Afterwards, oral, between 2.5 milligrams luseogliflozin and 5 milligrams luseogliflozin, to breakfast.

Detailed description

Usually for adults, 2.5 mg as luseogliflozin should be orally administered once daily before or after breakfast. When the effect is insufficient, the dose can be increased to 5 mg once daily while closely monitoring the clinical course.

Elderly

Because physiological function is generally impaired in elderly patients, luseogliflozin should be administered carefully while monitoring the conditions of patients.

Because detection of the symptoms of dehydration (including thirst) may be delayed in elderly patients, caution should be exercised.

Dosage considerations

Before or after breakfast.

Active ingredient

Luseogliflozin

Luseogliflozin lowers plasma glucose by inhibiting the activity of sodium-glucose cotransporter 2 (SGLT2) which is involved in reabsorption of glucose at renal proximal tubules and promoting the excretion of excessive glucose in blood into urine.

Read more about Luseogliflozin

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