Duodenal ulcer, chronic gastritis, peptic esophagitis

Active Ingredient: Sucralfate

Indication for Sucralfate

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Sucralfate is indicated in adults and adolescents over 14 years old for treatment of duodenal ulcer, chronic gastritis, peptic esophagitis.

For this indication, competent medicine agencies globally authorize below treatments:

4 gr in 4 divided doses per day

Route of admnistration


Defined daily dose

4 - 8 g

Dosage regimen

From 1 To 2 g 4 time(s) per day every day

Detailed description

The usual dose is 2 grams twice daily to be taken on rising and at bedtime, or 1 gram 4 times a day to be taken 1 hour before meals and at bedtime.

Maximum daily dose: 8 grams.

For ease of administration, sucralfate may be dispersed in 10-15 mL of water. Four to six weeks' treatment is usually needed for ulcer healing, but up to twelve weeks may be necessary in resistant cases.

Antacids may be used as required for relief of pain, but should not be taken half an hour before or after sucralfate.

Dosage considerations

Should be taken 1 hour before meals and at bedtime.

Active ingredient


Sucralfate forms an ulcer adherent complex with the proteinaceous exudate of the ulcer site. This property enables sucralfate to form a protective barrier over the ulcer lesion giving sustained protection against the penetration and action of gastric acid, pepsin and bile.

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