Myelodysplastic/myeloproliferative diseases (MDS/MPD) with platelet-derived growth factor receptor (PDGFR) gene re-arrangements

Active Ingredient: Imatinib

Indication for Imatinib

Population group: only adults (18 years old or older)

Imatinib is indicated for the treatment of adult patients with myelodysplastic/myeloproliferative diseases (MDS/MPD) associated with platelet-derived growth factor receptor (PDGFR) gene re-arrangements.

For this indication, competent medicine agencies globally authorize below treatments:

400 mg once daily

Route of admnistration

Oral

Defined daily dose

400 - 400 mg

Dosage regimen

From 400 To 400 mg once every day

Detailed description

The recommended dose of imatinib is 400 mg/day for adult patients with MDS/MPD.

Treatment duration: In the only clinical trial performed up to now, treatment with imatinib was continued until disease progression. At the time of analysis, the treatment duration was a median of 47 months (24 days-60 months).

Dosage considerations

The prescribed dose should be administered orally with a meal and a large glass of water to minimise the risk of gastrointestinal irritations.

Active ingredient

Imatinib

Imatinib is a protein-tyrosine kinase inhibitor which potently inhibits the Bcr-Abl tyrosine kinase at the in vitro, cellular and in vivo levels.

Read more about Imatinib

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