Moderate to severe symptomatic vulvar and vaginal atrophy (VVA) in post-menopausal women

Active Ingredient: Ospemifene

Indication for Ospemifene

Population group: women, only adults (18 years old or older)
Therapeutic intent: Curative procedure

For this indication, competent medicine agencies globally authorize below treatments:

60 mg once daily

Route of admnistration

Oral

Defined daily dose

60 - 60 mg

Dosage regimen

From 60 To 60 mg once every day

Detailed description

The recommended dose is one 60 mg tablet once daily with food taken at the same time each day.

If a dose is missed it should be taken with food as soon as the patient remembers. A double dose should not be taken in the same day.

Dosage considerations

One tablet should be swallowed whole once daily with food and should be taken at the same time each day.

Active ingredient

Ospemifene

Ospemifene and its major metabolite have an oestrogen like effect in the vagina increasing the cellular maturation and mucification of the vaginal epithelium. Ospemifene’s biological actions are mediated through the binding of ospemifene and its major metabolite to oestrogen receptors leading to activation of some oestrogenic pathways (agonism) and blockade of other (antagonism).

Read more about Ospemifene

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