Active Ingredient: Mitomycin
Intravesical administration for relapse prevention in superficial urinary bladder carcinoma after transurethral resection.
For this indication, competent medicine agencies globally authorize below treatments:
Intravesical
20 - 40 mg
From 20 To 40 mg once every 7 day(s)
In intravesical therapy, 20-40 mg of mitomycin in 20-40 ml of phosphate buffer pH 7.4 or sodium chloride (0.9%) solution, is instilled weekly into the bladder. The treatment period is 8 to 12 weeks. In the case of intravesical administration the urine pH should be higher than pH 6.
Intravesical
4 - 10 mg
From 4 To 10 mg once every 2 day(s)
Alternative dose recommendation in the prevention of recurrent superficial bladder tumours is 4-10 mg (0.06-0.15 mg/kg of body weight) instilled into the bladder though a urethral catheter 1 or 3 times per week.
The solution should be retained in the bladder for 1-2 hours.
Intravesical
0.06 - 0.15 mg per kg of body weight
From 0.06 To 0.15 mg per kg of body weight once every 2 day(s)
Alternative dose recommendation in the prevention of recurrent superficial bladder tumours is 4-10 mg (0.06-0.15 mg/kg of body weight) instilled into the bladder though a urethral catheter 1 or 3 times per week.
The solution should be retained in the bladder for 1-2 hours.
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