Magnetic resonance angiography (CE-MRA)

Active Ingredient: Gadofosveset

Indication for Gadofosveset

Population group: only adults (18 - 65 years old)

Gadofosveset is indicated for contrast-enhanced magnetic resonance angiography (CE-MRA) for visualisation of abdominal or limb vessels in adults only, with suspected or known vascular disease.

For this indication, competent medicine agencies globally authorize below treatments:

0.12 ml/kg

Route of admnistration


Defined daily dose

0.12 - 0.12 mL per kg of body weight

Dosage regimen

From 0.12 To 0.12 mL per kg of body weight once every day

Detailed description

Adults: 0.12 ml/kg body weight (equivalent to 0.03 mmol/kg)

Imaging time points

Dynamic imaging begins immediately upon injection. Steady state imaging can begin after the dynamic scan has been completed. In clinical trials, imaging was completed up to approximately one hour following injection.

Dosage considerations

It should be administered as a single intravenous bolus injection, manually, or by magnetic resonance injector (MR injector) over a period of time up to 30 seconds followed by a 25-30 ml normal saline flush.

Active ingredient


Gadofosveset is a formulation of a stable gadolinium diethylenetriaminepentaacetic acid (GdDTPA) chelate substituted with a diphenylcyclohexylphosphate group (gadofosveset trisodium), for use in magnetic resonance imaging (MRI). Gadofosveset binds reversibly to human serum albumin.

Read more about Gadofosveset

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