Moderate to severe manic episodes associated with bipolar disorders

Active Ingredient: Risperidone

Indication for Risperidone

Population group: only elderly (65 years old or older)

Risperidone is indicated for the treatment of moderate to severe manic episodes associated with bipolar disorders.

For this indication, competent medicine agencies globally authorize below treatments:

1-4 mg in 2 divided doses daily

Route of admnistration

Oral

Defined daily dose

1 - 4 mg

Dosage regimen

From 0.5 To 2 mg 2 time(s) per day every day

Loading dose

1 mg

Detailed description

A starting dose of 0.5 mg twice daily is recommended. This dosage can be individually adjusted with 0.5 mg twice daily increments to 1 to 2 mg twice daily. Since clinical experience in elderly is limited, caution should be exercised.

Dosage considerations

Risperidone is for oral use. Food does not affect the absorption of Risperidone.

Upon discontinuation, gradual withdrawal is advised. Acute withdrawal symptoms, including nausea, vomiting, sweating, and insomnia have very rarely been described after abrupt cessation of high doses of antipsychotic medicines. Recurrence of psychotic symptoms may also occur, and the emergence of involuntary movement disorders (such as akathisia, dystonia and dyskinesia) has been reported.

Active ingredient

Risperidone

Risperidone is a selective monoaminergic antagonist with unique properties. Although risperidone is a potent D2 antagonist, which is considered to improve the positive symptoms of schizophrenia, it causes less depression of motor activity and induction of catalepsy than classical antipsychotics.

Read more about Risperidone

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