Carcinoid tumor

Indication for Interferon, alfa-2b

Population group: Suitable for both men and women, only adults (18 - 65 years old)

For this indication, competent medicine agencies globally authorize below treatments:

3-9 million IU once every other day

Route of admnistration

Subcutaneous

Defined daily dose

3,000,000 - 9,000,000 [iU]

Dosage regimen

From 3,000,000 To 9,000,000 [iU] once every 2 day(s)

Detailed description

The usual dose is 5 million IU (3 to 9 million IU) administered subcutaneously three times a week (every other day). Patients with advanced disease may require a daily dose of 5 million IU. The treatment is to be temporarily discontinued during and after surgery. Therapy may continue for as long as the patient responds to interferon alfa-2b treatment.

Active ingredient

Recombinant interferon alfa-2b is a sterile, stable, formulation of highly purified interferon alfa-2b produced by recombinant DNA techniques. Interferons exert their cellular activities by binding to specific membrane receptors on the cell surface. Recombinant interferon alfa-2b has exhibited antiproliferative effects in studies employing both animal and human cell culture systems as well as human tumour xenografts in animals. It has demonstrated significant immunomodulatory activity in vitro.

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