Diabetes mellitus

Active Ingredient: Acarbose

Indication for Acarbose

Population group: only adults (18 years old or older)

Acarbose is recommended for the treatment of non-insulin dependent (NIDDM) diabetes mellitus in patients inadequately controlled on diet alone, or on diet and oral hypoglycaemic agents.

For this indication, competent medicine agencies globally authorize below treatments:

150-600 mg in 3 divided doses daily

Route of admnistration

Oral

Defined daily dose

150 - 600 mg

Dosage regimen

From 50 To 200 mg 3 time(s) per day every day

Detailed description

The recommended initial dose is 50mg three times a day. However, some patients may benefit from more gradual initial dose titration to minimise gastrointestinal side-effects. This may be achieved by initiating treatment at 50mg once or twice a day, with subsequent titration to a three times a day regimen.

If after six to eight weeks' treatment patients show an inadequate clinical response, the dosage may be increased to 100mg three times a day. A further increase in dosage to a maximum of 200mg three times a day may occasionally be necessary.

If distressing complaints develop in spite of strict adherence to the diet, the dose should not be increased further and if necessary should be reduced according to the severity of the side-effects and the clinical judgment of the prescriber.

Acarbose is intended for continuous long-term treatment.

Dosage considerations

Should be swallowed whole with a little liquid directly before the meal.

Active ingredient

Acarbose

Acarbose is an alpha-glucosidase inhibitors, used in the treatment of diabetes. Inhibitors of a-glucosidase retard the breakdown of carbohydrates in the food and reduce the increase in blood glucose levels, which occurs after each meal.

Read more about Acarbose

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