Relapsing remitting multiple sclerosis (MS)

Active Ingredient: Teriflunomide

Indication for Teriflunomide

Population group: only adults (18 years old or older)

Teriflunomide is indicated for the treatment of adult patients with relapsing remitting multiple sclerosis (MS).

For this indication, competent medicine agencies globally authorize below treatments:

14 mg once daily

Route of admnistration

Oral

Defined daily dose

14 - 14 mg

Dosage regimen

From 14 To 14 mg once every day

Detailed description

The recommended dose of teriflunomide is 14 mg once daily.

Active ingredient

Teriflunomide

Teriflunomide is an immunomodulatory agent with anti-inflammatory properties that selectively and reversibly inhibits the mitochondrial enzyme dihydroorotate dehydrogenase (DHO-DH), required for the de novo pyrimidine synthesis. As a consequence teriflunomide reduces the proliferation of dividing cells that need de novo synthesis of pyrimidine to expand. The exact mechanism by which teriflunomide exerts its therapeutic effect in MS is not fully understood, but this is mediated by a reduced number of lymphocytes.

Read more about Teriflunomide

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