Active Ingredient: Aumolertinib
Aumolertinib as monotherapy is indicated for the first-line treatment of adult patients with advanced non-small cell lung cancer (NSCLC) whose tumours have EGFR exon 19 deletions or exon 21 (L858R) substitution mutations.
For this indication, competent medicine agencies globally authorize below treatments:
For:
Oral, 110 milligrams aumolertinib, once daily.
The recommended dose of aumolertinib is 110 mg once a day.
This medicinal product should be continued until disease progression or unacceptable toxicity.
If a dose of aumolertinib is missed, it should be taken within the same day as soon as the patient remembers. However, if the next scheduled dose is due within 12 hours, then the missed dose must be skipped. The patient should not take two doses together to make up for a missed dose.
Dosing interruption and/or dose reduction or permanent discontinuation may be required based on individual safety and tolerability.
If dose reduction is necessary, then the dose should be reduced from 110 mg to 55 mg taken once daily.
Aumolertinib should be taken approximately at the same time each day.
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