Seizures in eclampsia

Active Ingredient: Magnesium sulfate

Indication for Magnesium sulfate

Population group: women, only adults (18 - 65 years old)
Therapeutic intent: Preventive action

Prevention of recurrent seizures in eclampsia.

For this indication, competent medicine agencies globally authorize below treatments:

2-5 g once

Route of admnistration

Intravenous

Defined daily dose

2 - 5 g

Dosage regimen

From 2 To 5 g once every day

Detailed description

A loading dose of 4g (16 mmols) of magnesium ions IV (20ml of a 20% solution) or in some cases 5g (20 mmols) og magnesium ions IV (25 ml of a 20% solution), given over 5-15 minutes, is followed by an infusion of 1g (4mmols)/h (5ml of a 20% solution) continued for 24h after the last fit.

Recurrent Convulsions: If convulsions recur, a further 2-4g (8-16 mmols) of magnesium ions (10-20 ml of a 20% solution,depending on the woman’s weight, 2g (8 mmols) if less than 70Kg) is given IV over 5 min.

Active ingredient

Magnesium sulfate

Magnesium sulfate is a saline purgative. It can be employed locally in various inflammatory conditions, due to its osmotic action.

Read more about Magnesium sulfate

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