Vitreomacular traction (VMT)

Active Ingredient: Ocriplasmin

Indication for Ocriplasmin

Population group: only adults (18 years old or older)

Ocriplasmin is indicated in adults for the treatment of vitreomacular traction (VMT), including when associated with macular hole of diameter less than or equal to 400 microns.

For this indication, competent medicine agencies globally authorize below treatments:

0.125 mg once

Route of admnistration

Intravitreal

Defined daily dose

0.13 - 0.13 mg

Dosage regimen

From 0.13 To 0.13 mg once every day for 1 day(s)

Detailed description

The recommended dose is 0.125 mg (0.1 mL of the diluted solution) administered by intravitreal injection to the affected eye once as a single dose. Each vial should only be used once and for the treatment of a single eye. Treatment with ocriplasmin in the other eye is not recommended concurrently or within 7 days of the initial injection in order to monitor the post-injection course including the potential for decreased vision in the injected eye. Repeated administration in the same eye is not recommended.

Dosage considerations

The injection needle should be inserted 3.5-4.0 mm posterior to the limbus aiming towards the centre of the vitreous cavity avoiding the horizontal meridian.

Active ingredient

Ocriplasmin

Ocriplasmin has a proteolytic activity against protein components of the vitreous body and the vitreoretinal interface (VRI) (e.g. laminin, fibronectin and collagen) and aims to dissolve the protein matrix responsible for the abnormal vitreomacular adhesion (VMA).

Read more about Ocriplasmin

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