Raised intracranial pressure, cerebral oedema

Active Ingredient: Mannitol

Indication for Mannitol

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

Reduction of intracranial pressure and cerebral oedema, when the blood-barrier is intact.

For this indication, competent medicine agencies globally authorize below treatments:

1.5-2.0 g/kg

Route of admnistration


Defined daily dose

1.5 - 2 g per kg of body weight

Dosage regimen

From 1.5 To 2 g per kg of body weight once every day

Detailed description

The usual dose is 1.5 to 2 g/kg, infused over 30 to 60 minutes. When used preoperatively, the dose should be administered 1 to 1.5 hours before surgery to obtain the maximum effect.

Dosage considerations

This hypertonic solution should be administered via a large peripheral or, preferably, a central vein. Rapid infusion in peripheral veins may be harmful.

Active ingredient


Mannitol is a naturally occurring sugar alcohol used clinically primarily for its osmotic diuretic properties.

Read more about Mannitol

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