Terbutaline is a selective beta2-adrenergic agonist recommended for the relief of bronchospasm in bronchial asthma and other bronchopulmonary disorders in which bronchospasm or reversible airways obstruction is a complicating factor.
For this indication, competent medicine agencies globally authorize below treatments:
For: Children Adolescents Adults (18-64) Elders (65+)
Respiratory (Inhalation), 0.5 milligrams, 1 to 4 times daily. The maximum allowed total dose is 2 milligrams daily.
One inhalation (0.5 mg) as required. Not more than 4 inhalations should be required in any 24-hour period.
The duration of action of a single dose is up to 6 hours.
For: Children
Oral, 2.5 milligrams, 2 to 3 times daily.
The starting dose should normally be 2.5mg (half a tablet) 2 times in 24 hours. However, in some patients, the dose may need to be increased to 2.5mg 3 times in 24 hours.
For: Adolescents Adults (18-64) Elders (65+)
Oral, 2.5 milligrams, 3 times daily, over the duration of 1 to 2 weeks. Afterwards, oral, 5 milligrams, 3 times daily.
During the first 1-2 weeks, 2.5 mg (half a tablet) 3 times in a 24-hour period is recommended. The dose may then be increased to 5 mg (1 tablet) 3 times in a 24-hour period to achieve adequate bronchodilation.
For: Adults (18-64) Elders (65+)
Intravenous, between 0.25 and 0.5 milligrams, 1 to 4 times daily.
When a rapid therapeutic response is required, terbutaline can be administered by i.v. bolus. When given as an i.v. bolus the injection must be made slowly noting patient response.
0.25-0.5 mg up to four times a day.
For: Adults (18-64) Elders (65+)
Subcutaneous, between 0.25 and 0.5 milligrams, 1 to 4 times daily.
When a rapid therapeutic response is required, terbutaline can be administered by subcutaneous route.
0.25-0.5 mg up to four times a day.
For: Adults (18-64) Elders (65+)
Intramuscular, between 0.25 and 0.5 milligrams, 1 to 4 times daily.
When a rapid therapeutic response is required, terbutaline can be administered by intramuscular route.
0.25-0.5 mg up to four times a day.
For: Children
Intravenous, 0.01 milligrams per kilogram of body weight, one dose.
When a rapid therapeutic response is required, terbutaline can be administered by i.v. bolus. When given as an i.v. bolus the injection must be made slowly noting patient response.
Children 2-15 years: 0.01 mg/kg body weight to a maximum of 0.3 mg total.
| Age | Average weight | mg | |
|---|---|---|---|
| kg | (lb) | terbutaline | |
| <3 | 10 | (22) | 0.1 |
| 3 | 15 | (33) | 0.15 |
| 6 | 20 | (44) | 0.2 |
| 8 | 25 | (55) | 0.25 |
| 10+ | 30+ | (66+) | 0.3 |
For: Children
Subcutaneous, 0.01 milligrams per kilogram of body weight, one dose.
When a rapid therapeutic response is required, terbutaline can be administered by subcutaneous route.
Children 2-15 years: 0.01 mg/kg body weight to a maximum of 0.3 mg total.
| Age | Average weight | mg | |
|---|---|---|---|
| kg | (lb) | terbutaline | |
| <3 | 10 | (22) | 0.1 |
| 3 | 15 | (33) | 0.15 |
| 6 | 20 | (44) | 0.2 |
| 8 | 25 | (55) | 0.25 |
| 10+ | 30+ | (66+) | 0.3 |
For: Children
Intramuscular, 0.01 milligrams per kilogram of body weight, one dose.
When a rapid therapeutic response is required, terbutaline can be administered by intramuscular route.
Children 2-15 years: 0.01 mg/kg body weight to a maximum of 0.3 mg total.
| Age | Average weight | mg | |
|---|---|---|---|
| kg | (lb) | terbutaline | |
| <3 | 10 | (22) | 0.1 |
| 3 | 15 | (33) | 0.15 |
| 6 | 20 | (44) | 0.2 |
| 8 | 25 | (55) | 0.25 |
| 10+ | 30+ | (66+) | 0.3 |
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