Active Ingredient: Spesolimab
Spesolimab is indicated for the treatment of flares in adult patients with generalised pustular psoriasis (GPP) as monotherapy.
For this indication, competent medicine agencies globally authorize below treatments:
For:
Intravenous, 900 milligrams spesolimab, one dose, over the duration of 1 week. Afterwards, intravenous, 900 milligrams spesolimab, one dose.
The recommended dose is a single dose of 900 mg (2 vials of 450 mg) administered as an intravenous infusion.
If flare symptoms persist, an additional 900 mg dose may be administered 1 week after the initial dose.
Clinical data for treatment of subsequent flares is very limited.
Clinical data for concomitant use of other GPP treatments with spesolimab is limited. Spesolimab should not be used in combination with other GPP treatments, e.g. systemic immunosuppressants, to treat a flare.
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