Active Ingredient: Atogepant
Atogepant is indicated for prophylaxis of migraine in adults who have at least 4 migraine days per month.
For this indication, competent medicine agencies globally authorize below treatments:
For:
Oral, 60 milligrams atogepant, once daily.
The recommended dose is 60 mg atogepant once daily.
A missed dose should be taken as soon as it is remembered. If it is forgotten for an entire day, the missed dose should be skipped and the next dose taken as scheduled.
Dosing modifications for concomitant use of specific medicinal products are provided in the following table.
Dose modifications for interactions:
| Dose modifications | Recommended once daily dose |
|---|---|
| Strong CYP3A4 inhibitors | 10 mg |
| Strong OATP inhibitors | 10 mg |
Population pharmacokinetic modelling suggests no clinically significant pharmacokinetic differences between elderly and younger subjects. No dose adjustment is needed in elderly patients.
It can be taken with or without meals.
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