Overactive bladder

Active Ingredient: Trospium

Indication for Trospium

Population group: only adults (18 years old or older)

Symptomatic treatment of urge incontinence and/or increased urinary frequency and urgency as may occur in patients with overactive bladder (e.g. idiopathic or neurologic detrusor overactivity).

For this indication, competent medicine agencies globally authorize below treatments:

40 mg in 2 divided doses daily

Route of admnistration

Oral

Defined daily dose

40 - 40 mg

Dosage regimen

From 20 To 20 mg 2 time(s) per day every day

Detailed description

20 mg twice daily (40 mg of trospium chloride per day).

The need for continued treatment should be reassessed at regular intervals of 3-6 months.

Patients with renal impairment: In patients with severe renal impairment (creatinine clearance between 10 and 30 ml/min.1.73 m²), the recommended dosage is 20 mg per day or every second day.

Active ingredient

Trospium

Trospium is an antispasmodic, antimuscarinic agent indicated for the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and urinary frequency. Receptor assays showed that trospium has negligible affinity for nicotinic receptors as compared to muscarinic receptors at concentrations obtained from therapeutic doses. Trospium antagonizes the effect of acetylcholine on muscarinic receptors in cholinergically innervated organs. Its parasympatholytic action reduces the tonus of smooth muscle in the bladder.

Read more about Trospium

Related medicines

Develop a tailored medication plan for your case, considering factors such as age, gender, and health history

Ask the Reasoner

Liability Disclaimer : RxReasoner has utilized reasonable care in providing content and services that are accurate, complete and up to date. However, RxReasoner does not accept any responsibility or liability about it. The content and services of RxReasoner are for informational purposes only and they are not intended to be a substitute for the knowledge, expertise, skill, and judgment of physicians, pharmacists, nurses, or other healthcare professionals involved in patient care. RxReasoner offers no medical advice. Users are responsible for the use of the provided content. A shown indication or treatment should not be construed to indicate that the medication is safe, appropriate, or effective in any given patient or under any particular circumstances. The absence of an indication or treatment should not roule out the existence of other appropriate medications. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition or medicament. RxReasoner is not liable for any damages allegedly sustained arising out of the use of its content and services.