Inhibition of intraoperative miosis, post-operative trabeculoplasty inflammation in the anterior segment of the eye

Active Ingredient: Flurbiprofen

Indication for Flurbiprofen

Population group: only adults (18 years old or older)
Therapeutic intent: Curative procedure

Flurbiprofen is indicated for:

  • the inhibition of intraoperative miosis. Flurbiprofen does not have intrinsic mydriatic properties and does not replace mydriatic agents.
  • the management of post-operative and post-laser trabeculoplasty inflammation in the anterior segment of the eye in patients in whom steroid therapy is not recommended.

For this indication, competent medicine agencies globally authorize below treatments:

1 drop every half hour starting 2 hours before surgery and 24 after surgery 1 drop four times daily


Dosage regimens

Ophthalmic, 1 drops flurbiprofen, daily, 4 doses in total. Afterwards, ophthalmic, 1 drops flurbiprofen, daily, 4 doses in total, over the duration of 1 to 3 weeks.

Detailed description

For the inhibition of intraoperative miosis, 1 drop is instilled every half hour starting 2 hours before surgery. The final drop should be given not less than 30 minutes before surgery.

To control post-operative and post-laser trabeculoplasty inflammation the dosing regimen above should be followed. Beginning twenty-four hours after surgery, one drop is administered four times daily for at least one week after laser trabeculoplasty or for two to three weeks after other surgery.

Dosage considerations

Flurbiprofen eye drops are administered topically by instillation into the conjunctival sac.

In accordance with standard practice, other topical medication should not be co-administered with flurbiprofen. When administering other topical medications, a minimum interval of 5 minutes between instillations is recommended.

Active ingredient


Flurbiprofen is a propionic acid derivative NSAID which acts through inhibition of prostaglandin synthesis. In humans flurbiprofen has potent analgesic, antipyretic and anti-inflammatory properties.

Read more about Flurbiprofen

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