Active Ingredient: Amikacin
Amikacin is indicated for the treatment of non-tuberculous mycobacterial (NTM) lung infections caused by Mycobacterium avium Complex (MAC) in adults with limited treatment options who do not have cystic fibrosis.
Consideration should be given to official guidance on the appropriate use of antibacterial agents.
Amikacin should be used in conjunction with other antibacterial agents active against Mycobacterium avium Complex lung infections.
For this indication, competent medicine agencies globally authorize below treatments:
For:
Respiratory (Inhalation), 590 milligrams amikacin, once daily.
The recommended dose is 590 mg administered once daily, by oral inhalation.
Treatment with inhaled liposomal amikacin, as part of a combination antibacterial regimen, should be continued for 12 months after sputum culture conversion.
Treatment with inhaled liposomal amikacin should not continue beyond a maximum of 6 months if sputum culture conversion (SCC) has not been confirmed by then.
The maximum duration of treatment with inhaled liposomal amikacin should not exceed 18 months.
If a daily dose of amikacin is missed, the next dose should be administered the next day. A double dose should not be given to make up for the missed dose.
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