Prevention of influenza

Active Ingredient: Zanamivir

Indication for Zanamivir

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 - 65 years old)

Zanamivir is indicated for post-exposure prophylaxis of influenza A and B in adults and children (≥5 years) following contact with a clinically diagnosed case in a household. In exceptional circumstances, zanamivir may be considered for seasonal prophylaxis of influenza A and B during a community outbreak (e.g. in case of a mismatch between circulating and vaccine strains and a pandemic situation).

For this indication, competent medicine agencies globally authorize below treatments:

10 mg once daily

Route of admnistration

Respiratory (Inhalation)

Defined daily dose

10 - 10 mg

Dosage regimen

From 10 To 10 mg once every day for 10 day(s)

Detailed description

Post-exposure prophylaxis: The recommended dose of zanamivir for prevention of influenza, following close contact with an individual, is two inhalations (2 × 5 mg) once daily for 10 days. Therapy should begin as soon as possible and within 36 hours of exposure to an infected person.

Seasonal prophylaxis: The recommended dose of zanamivir for prevention of influenza during a community outbreak is 2 inhalations (2 × 5 mg) once daily for up to 28 days.

Active ingredient


Zanamivir is a selective inhibitor of neuraminidase, the influenza virus surface enzyme. Neuraminidase inhibition occurred in vitro at very low zanamivir concentrations (50% inhibition at 0.64nM–7.9nM against influenza A and B strains).

Read more about Zanamivir

Related medicines

Develop a tailored medication plan for your case, considering factors such as age, gender, and health history

Ask the Reasoner

Liability Disclaimer : RxReasoner has utilized reasonable care in providing content and services that are accurate, complete and up to date. However, RxReasoner does not accept any responsibility or liability about it. The content and services of RxReasoner are for informational purposes only and they are not intended to be a substitute for the knowledge, expertise, skill, and judgment of physicians, pharmacists, nurses, or other healthcare professionals involved in patient care. RxReasoner offers no medical advice. Users are responsible for the use of the provided content. A shown indication or treatment should not be construed to indicate that the medication is safe, appropriate, or effective in any given patient or under any particular circumstances. The absence of an indication or treatment should not roule out the existence of other appropriate medications. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition or medicament. RxReasoner is not liable for any damages allegedly sustained arising out of the use of its content and services.