In patients, children or adults with severe congenital, cyclic, or idiopathic neutropenia with an absolute neutrophil count (ANC) of ≤0.5 × 109/L, and a history of severe or recurrent infections, long term administration of filgrastim is indicated to increase neutrophil counts and to reduce the incidence and duration of infection-related events.
For this indication, competent medicine agencies globally authorize below treatments:
12 - 12 ug per kg of body weight
From 12 To 12 ug per kg of body weight once every day
The recommended starting dose is 1.2 MU (12 μg)/kg/day as a single dose or in divided doses.
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