Congenital neutropenia

Active Ingredient: Filgrastim

Indication for Filgrastim

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

In patients, children or adults with severe congenital, cyclic, or idiopathic neutropenia with an absolute neutrophil count (ANC) of ≤0.5 × 109/L, and a history of severe or recurrent infections, long term administration of filgrastim is indicated to increase neutrophil counts and to reduce the incidence and duration of infection-related events.

For this indication, competent medicine agencies globally authorize below treatments:

12 ug/kg once a day

Route of admnistration


Defined daily dose

12 - 12 ug per kg of body weight

Dosage regimen

From 12 To 12 ug per kg of body weight once every day

Detailed description

The recommended starting dose is 1.2 MU (12 μg)/kg/day as a single dose or in divided doses.

Active ingredient


Filgrastim causes marked increases in peripheral blood neutrophil counts within 24 hours, with minor increases in monocytes.

Read more about Filgrastim

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