Moderate to severe plaque psoriasis

Active Ingredient: Brodalumab

Indication for Brodalumab

Population group: only adults (18 years old or older)

Brodalumab is indicated for the treatment of moderate to severe plaque psoriasis in adult patients who are candidates for systemic therapy.

For this indication, competent medicine agencies globally authorize below treatments:

210 mg once every week

Route of admnistration

Subcutaneous

Defined daily dose

210 - 210 mg

Dosage regimen

From 210 To 210 mg once every 7 day(s)

Detailed description

The recommended dose is 210 mg administered by subcutaneous injection at weeks 0, 1, and 2 followed by 210 mg every 2 weeks.

Consideration should be given to discontinuing treatment in patients who have shown no response after 12-16 weeks of treatment. Some patients with initial partial response may subsequently improve with continued treatment beyond 16 weeks.

Active ingredient

Brodalumab

Brodalumab is a recombinant fully human monoclonal immunoglobulin IgG2 antibody that binds with high affinity to human IL-17RA and blocks the biological activities of the pro-inflammatory cytokines IL-17A, IL-17F, IL-17A/F heterodimer and IL-25, resulting in inhibition of the inflammation and clinical symptoms associated with psoriasis.

Read more about Brodalumab

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