Promotion of controlled superovulation

Active Ingredient: Chorionic gonadotrophin (human)

Indication for Chorionic gonadotrophin (human)

Population group: women, only adults (18 - 65 years old)

In combination with FSH or HMG, promotion of controlled superovulation in medically assisted reproduction programmes.

For this indication, competent medicine agencies globally authorize below treatments:

5000-10000 IU once

Route of admnistration

Intramuscular

Defined daily dose

5,000 - 10,000 [iU]

Dosage regimen

From 5,000 To 10,000 [iU] once every day

Detailed description

5,000–10,000 IU hCG 30-40 hours after the last FSH or HMG injection. Chorionic gonadotrophin should not be administered if the following criteria have not been met: at least 3 follicles greater than 17mm in diameter are present with 17ß estradiol levels of at least 3500 pmol/L (920 picogram/ml). Oocyte collection is carried out 32-36 hours after the hCG injection.

As luteal phase support, two to three injections of 1,000 to 3,000 IU hCG each may be given within nine days of ovulation or embryo transfer, for example on day 3, 6 and 9 after ovulation induction or embryo transfer.

Active ingredient

Chorionic gonadotrophin (human)

Human chorionic gonadotrophin stimulates the steroidogenesis in the gonads by virtue of a biological effect similar to that of LH (Luteinizing hormone, which is the same as interstitial cell stimulating hormone).

Read more about Chorionic gonadotrophin (human)

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