Influenza

Active Ingredient: Zanamivir

Indication for Zanamivir

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 - 65 years old)

Zanamivir is indicated for treatment of both influenza A and B in adults and children (≥5 years) who present with symptoms typical of influenza when influenza is circulating in the community.

For this indication, competent medicine agencies globally authorize below treatments:

20 mg in 2 divided doses daily

Route of admnistration

Respiratory (Inhalation)

Defined daily dose

20 - 20 mg

Dosage regimen

From 10 To 10 mg 2 time(s) per day every day

Detailed description

Treatment should begin as soon as possible, within 48 hours after onset of symptoms for adults, and within 36 hours after onset of symptoms for children.

Zanamivir is for administration to the respiratory tract by oral inhalation only.

The recommended dose of zanamivir for treatment of influenza in adults and children from the age of 5 years is two inhalations (2 × 5 mg) twice daily for five days, providing a total daily inhaled dose of 20 mg.

Active ingredient

Zanamivir

Zanamivir is a selective inhibitor of neuraminidase, the influenza virus surface enzyme. Neuraminidase inhibition occurred in vitro at very low zanamivir concentrations (50% inhibition at 0.64nM–7.9nM against influenza A and B strains).

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