Platinum-sensitive relapsed high grade serous epithelial ovarian, fallopian tube, or primary peritoneal cancer

Active Ingredient: Niraparib

Indication for Niraparib

Population group: only adults (18 years old or older)
Therapeutic intent: Curative procedure

Niraparib is indicated as monotherapy for the maintenance treatment of adult patients with platinum-sensitive relapsed high grade serous epithelial ovarian, fallopian tube, or primary peritoneal cancer who are in response (complete or partial) to platinum-based chemotherapy.

For this indication, competent medicine agencies globally authorize below treatments:

300 mg once daily

For:

Dosage regimens

Oral, 300 milligrams niraparib, once daily.

Detailed description

The dose is 300 mg once daily.

Patients should be encouraged to take their dose at approximately the same time each day. Bedtime administration may be a potential method for managing nausea.

It is recommended that treatment should be continued until disease progression.

Missing dose

If patients miss a dose, they should take their next dose at its regularly scheduled time.

Elderly

No dose adjustment is necessary for elderly patients (≥65 years). There are limited clinical data in patients aged 75 or over.

Dosage considerations

Niraparib can be taken without regard to meals.

Active ingredient

Niraparib

Niraparib is an inhibitor of poly(ADP-ribose) polymerase (PARP) enzymes, PARP-1 and PARP-2, which play a role in DNA repair.

Read more about Niraparib

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