Gastroesophageal reflux disease

Active Ingredient: Ranitidine

Indication for Ranitidine

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old)

For this indication, competent medicine agencies globally authorize below treatments:

5-10 mg/kg in 2 divided doses daily

Route of admnistration

Oral

Defined daily dose

5 - 10 mg per kg of body weight

Dosage regimen

From 2.5 To 5 mg per kg of body weight 2 time(s) per day every day

Detailed description

The recommended oral dose for the treatment of gastro-oesophageal reflux in children is 5 mg/kg/day to 10 mg/kg/day administered as two divided doses to a maximum of 600 mg (the maximum dose is likely to apply to heavier children or adolescents with severe symptoms).

Active ingredient

Ranitidine

Ranitidine is a specific rapidly acting histamine H2-antagonist. It inhibits basal and stimulated secretion of gastric acid, reducing both the volume and the acid and pepsin content of the secretion. Ranitidine has a relatively long duration of action and so a single 150 mg dose effectively suppresses gastric acid secretion for twelve hours.

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