Active Ingredient: Tezepelumab
Tezepelumab is indicated as an add-on maintenance treatment in adults and adolescents 12 years and older with severe asthma who are inadequately controlled despite high dose inhaled corticosteroids plus another medicinal product for maintenance treatment.
For this indication, competent medicine agencies globally authorize below treatments:
For:
Subcutaneous, 210 milligrams tezepelumab, once every 4 weeks.
The recommended dose is 210 mg of tezepelumab by subcutaneous injection every 4 weeks.
Tezepelumab is intended for long-term treatment. A decision to continue the therapy should be made at least annually based on the patient’s level of asthma control.
If a dose is missed, the dose should be administered as soon as possible. Thereafter, the patient can resume dosing on the scheduled day of administration. If the next dose is already due, then administer as planned. A double dose must not be administered.
No dose adjustment is required for elderly patients.
Tezepelumab injection should be injected into the thigh or abdomen, except for the 5 cm around the navel. If a healthcare professional or caregiver administers the injection, the upper arm can also be used. A patient should not self-inject in the arm. It should not be injected into areas where the skin is tender, bruised, erythematous, or hardened. It is recommended to rotate the injection site with each injection.
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