Addisonian pernicious anaemia, cobalamin deficiency, megaloblastic anemia due to vitamin B12 deficiency

Active Ingredient: Vitamin B12

Indication for Vitamin B12

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

For this indication, competent medicine agencies globally authorize below treatments:

Initially 250-1,000 micrograms on alternate days for 1-2 weeks and then 1,000 micrograms once every 2-3 months

Route of admnistration

Intramuscular

Defined daily dose

250 - 1,000 ug

Dosage regimen

From 250 To 1,000 ug once every 2 day(s)

Detailed description

Addisonian pernicious anaemia and other macrocytic anaemias without neurological involvement:

Initially: 250 micrograms to 1,000 micrograms intramuscularly on alternate days for one or two weeks then 250 micrograms weekly until blood count is normal.

Maintenance: 1,000 micrograms every two or three months.

Addisonian pernicious anaemia and other macrocytic anaemias with neurological involvement:

Initially: 1,000 micrograms on alternate days as long as improvement continues.

Maintenance: 1,000 micrograms every two months.

Active ingredient

Vitamin B12

Hydroxocobalamin is used in the treatment and prevention of Vitamin B12 deficiency. For adults, the daily requirement of Vitamin B12 is probably about 1 to 2 micrograms and this amount is present in most normal diets. However, Vitamin B12 only occurs in animal products, not in vegetables, and therefore strict vegetarian or vegan diets that exclude dairy products may provide an inadequate amount, although a deficiency may not be apparent for many years.

Read more about Vitamin B12

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