Neuroendocrine tumours

Active Ingredient: Lanreotide

Indication for Lanreotide

Population group: only adults (18 years old or older)
Therapeutic intent: Curative procedure

Lanreotide is indicated for the treatment of symptoms associated with neuroendocrine (particularly carcinoid) tumours.

For this indication, competent medicine agencies globally authorize below treatments:

60-120 mg every 28 days

For:

Dosage regimens

Subcutaneous, between 60 milligrams lanreotide and 120 milligrams lanreotide, once every 28 days. The maximum allowed total dose is 120 milligrams lanreotide every 28 days.

Detailed description

The recommended starting dose is 60 to 120 mg administered every 28 days.

The dose should be adjusted according to the degree of symptomatic relief obtained.

Dosage considerations

Lanreotide is administered by deep subcutaneous injection in the superior external quadrant of the buttock or in the upper outer thigh.

For patients who receive a stable dose of lanreotide, and after appropriate training, the injection may be administered either by the patient or by a trained person. In case of self-injection, the injection should be given in the upper outer thigh.

The decision regarding administration by the patient or a trained person should be taken by a healthcare professional.

Regardless of the injection site, the skin should not be folded and the needle should be inserted rapidly and to its full length, perpendicularly to the skin.

The injection site should alternate between the right and left side.

30 mg once every 14 days

For:

Dosage regimens

Regimen A :

Intramuscular, 30 milligrams lanreotide, once every 14 days.

Regimen B, in the case that there is absent response to treatment :

Intramuscular, 30 milligrams lanreotide, once every 14 days. Afterwards, intramuscular, 30 milligrams lanreotide, once every 7 to 10 days.

Detailed description

Initially, one intramuscular injection of 30 mg should be given every 14 days. The frequency of subsequent injections may be varied in accordance with the individual patient's response (as judged by a reduction in symptoms and/or a reduction in GH and/or IGF-1 levels) such that injections can be given every 7 to 10 days as necessary.

Active ingredient

Lanreotide

Lanreotide is an octapeptide analogue of natural somatostatin. Like somatostatin, lanreotide is an inhibitor of various endocrine, neuroendocrine, exocrine and paracrine functions.

Read more about Lanreotide

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