Cancer of prostate

Active Ingredient: Cyproterone

Indication for Cyproterone

Population group: men, only adults (18 - 65 years old)
Therapeutic intent: Palliative intent

For this indication, competent medicine agencies globally authorize below treatments:

300 mg once weekly


Route of admnistration


Defined daily dose

300 - 300 mg

Dosage regimen

From 300 To 300 mg once every 7 day(s)

Detailed description

The usual initial and maintenance dose of cyproterone is one weekly intramuscular injection of 3 mL (300 mg).

For orchiectomized patients, the recommended dose is one intramuscular injection of 3 mL (300 mg) every two weeks.

The therapy should not be interrupted nor the dosage reduced after remission or improvement occurs.

Active ingredient


Cyproterone acetate acts as an antiandrogen by blocking androgen receptors. It also has progestogenic activity, which exerts a negative feedback effect on hypothalamic receptors, so leading to a reduction in gonadotrophin release, and hence to diminished production of testicular androgens. Sexual drive and potency are reduced and gonadal function is inhibited.

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