In the treatment of idiopathic Parkinson’s Disease, bromocriptine has been used both alone and in combination with Levodopa in the management of previously untreated patients and those disabled by ‘on-off’ phenomena. Bromocriptine has been used with occasional benefit in patients who do not respond to or are unable to tolerate Levodopa and those whose response to Levodopa is declining.
For this indication, competent medicine agencies globally authorize below treatments:
Oral
1 - 30 mg
From 0.25 To 7.5 mg 4 time(s) per day every day
Introduce bromocriptine gradually, as follows: Week 1: 1mg to 1.25mg at bed time. Week 2: 2mg to 2.5mg at bed time. Week 3: 2.5mg twice daily. Week 4: 2.5mg three times daily. Thereafter take three times a day increasing by 2.5mg every 3 to 14 days, depending on the patient’s response. Continue until the optimum dose is reached. This will usually be between 10mg and 30mg daily. Daily doses should not exceed 30 mg. In patients already receiving Levodopa the dosage of this drug may gradually be decreased while the dosage daily of bromocriptine is increased until the optimum balance is determined.
Bromocriptine should always be taken with food.
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