Active immunisation against smallpox

Active Ingredient: Smallpox, live attenuated

Indication for Smallpox, live attenuated

Population group: only adults (18 years old or older)
Therapeutic intent: Preventive action

For this indication, competent medicine agencies globally authorize below treatments:

0.5 ml

Route of admnistration

Subcutaneous

Defined daily dose

0.5 - 0.5 mL

Dosage regimen

From 0.5 To 0.5 mL once every day

Detailed description

Primary vaccination (individuals previously not vaccinated against smallpox)

A first dose of 0.5 ml should be administered on an elected date.

A second dose of 0.5 ml should be administered no less than 28 days after the first dose.

Booster vaccination (individuals previously vaccinated against smallpox)

There are inadequate data to determine the appropriate timing of booster doses. If a booster dose is considered necessary then a single dose of 0.5 ml should be administered.

Special population

Immunocompromised patients (e.g. HIV infected, patients under immunosuppressive therapy) who have been previously vaccinated against smallpox should receive two booster doses. The second booster vaccination should be given no less than 28 days after the first dose.

Dosage considerations

Immunisation should be carried out by subcutaneous injection, preferably into the upper arm (deltoid).

Active ingredient

Smallpox, live attenuated

Smallpox vaccine is indicated for active immunization against smallpox disease for persons determined to be at high risk for smallpox infection.

Read more about Smallpox, live attenuated

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