Neutropenia after cytotoxic chemotherapy for malignancy

Active Ingredient: Lipegfilgrastim

Indication for Lipegfilgrastim

Population group: only adults (18 years old or older)

Lipegfilgrastim is indicated in adults for reduction in the duration of neutropenia and the incidence of febrile neutropenia in patients treated with cytotoxic chemotherapy for malignancy (with the exception of chronic myeloid leukaemia and myelodysplastic syndromes).

For this indication, competent medicine agencies globally authorize below treatments:

6 mg once

Route of admnistration

Subcutaneous

Defined daily dose

6 - 6 mg

Dosage regimen

From 6 To 6 mg once every day for 1 day(s)

Detailed description

One 6 mg dose of lipegfilgrastim is recommended for each chemotherapy cycle, given approximately 24 hours after cytotoxic chemotherapy.

Dosage considerations

It should be given approximately 24 hours after cytotoxic chemotherapy. The injections should be given into the abdomen, upper arm or thigh.

Active ingredient

Lipegfilgrastim

Lipegfilgrastim is a sustained duration form of filgrastim due to decreased renal clearance. Lipegfilgrastim binds to human the G-CSF receptor like filgrastim and pegfilgrastim. Human G-CSF is a glycoprotein that regulates the production and release of functional neutrophils from the bone marrow.

Read more about Lipegfilgrastim

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