Scabies, crab lice

Active Ingredient: Permethrin

Indication for Permethrin

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Permethrin is indicated for the treatment of scabies in adults and children >2 months of age, and crab lice in adults.

For this indication, competent medicine agencies globally authorize below treatments:

Up to 30 g

Route of admnistration

Cutaneous

Defined daily dose

30 g

Dosage regimen

30 g once every day

Detailed description

For treatment of scabies

Adults should apply the cream uniformly to the whole body including the neck, palms of the hands and soles of the feet. The head and face can be spared unless scabies efflorescences are present in this region. On application, the areas between the fingers and toes (also under the finger- and toe-nails), the wrists, elbows, armpits, external genitalia and the buttocks should be especially carefully treated.

For treatment of crab lice in adults

Sufficient cream should be applied to cover the pubic region, peri-anal (around the anus), inner thighs down to the knees and any hair that grows up from the pubic area to the chest/stomach. For treatment of crab lice in adults, the cream should be left on the skin for 24 hours, after which the treatment areas should be washed thoroughly. Any facial hair (beards, moustaches) and eyelashes should be checked for the presence of live lice and eggs. Cream should be applied to any facial hair, carefully avoiding eyes. If live lice or eggs are found on the eyelashes they should be removed carefully using tweezers. Cream should not be applied to the eyelashes because the cream can cause moderate eye irritation.

Active ingredient

Permethrin

The principal physiological action in insects (lice) exposed to permethrin is induction of electrochemical abnormalities across the membranes of excitable cells, leading to sensory hyperexcitability, inco-ordination and prostration. It is assumed that the mode of action against arachnids (mites) is similar.

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