Acute treatment of the headache phase of migraine attacks with or without aura in adults.
For this indication, competent medicine agencies globally authorize below treatments:
10 - 20 mg
From 5 To 10 mg 2 time(s) per day every day
The recommended dose is 10 mg.
Redosing: Doses should be separated by at least two hours; no more than two doses should be taken in any 24-hour period.
For headache recurrence within 24 hours: If headache returns after relief of the initial attack, one further dose may be taken. The above dosing limits should be observed.
After non-response: The effectiveness of a second dose for treatment of the same attack, when an initial dose is ineffective, has not been examined in controlled trials. Therefore, if a patient does not respond to the first dose, a second dose should not be taken for the same attack.
Rizatriptan should not be used prophylactically.
The oral tablets should be swallowed whole with liquid.
The absorption of rizatriptan is delayed by approximately 1 hour when administered together with food. Therefore, onset of effect may be delayed when rizatriptan is administered in the fed state.