Active Ingredient: Nevirapine
Nevirapine is indicated in combination with other anti-retroviral medicinal products for the treatment of HIV-1 infected children of any age.
For this indication, competent medicine agencies globally authorize below treatments:
Oral
150 - 300 mg per m² of body surface area (BSA)
From 75 To 150 mg per m² of body surface area (BSA) 2 time(s) per day every day
150 mg per m² of body surface area (BSA)
300 mg per m² of body surface area (BSA)
The total daily dose should not exceed 400 mg for any patient. Nevirapine may be dosed in paediatric patients either by body surface area (BSA) or by body weight as follows:
By BSA using the Mosteller formula the recommended oral dose for paediatric patients of all ages is 150 mg/m² once daily for two weeks followed by 150 mg/m² twice daily thereafter.
Oral
4 - 8 mg per kg of body weight
From 2 To 4 mg per kg of body weight 2 time(s) per day every day
4 mg per kg of body weight
8 mg per kg of body weight
The total daily dose should not exceed 400 mg for any patient. Nevirapine may be dosed in paediatric patients either by body surface area (BSA) or by body weight as follows:
By weight the recommended oral dose for paediatric patients up to 8 years of age is 4 mg/kg once daily for two weeks followed by 7 mg/kg twice daily thereafter. For patients 8 years and older the recommended dose is 4 mg/kg once daily for two weeks followed by 4 mg/kg twice daily thereafter.
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