Non-small cell lung cancer

Active Ingredient: Docetaxel

Indication for Docetaxel

Population group: only adults (18 years old or older)

Docetaxel is indicated for the treatment of patients with locally advanced or metastatic non-small cell lung cancer after failure of prior chemotherapy.

Docetaxel in combination with cisplatin is indicated for the treatment of patients with unresectable, locally advanced or metastatic non-small cell lung cancer, in patients who have not previously received chemotherapy for this condition.

For this indication, competent medicine agencies globally authorize below treatments:

75 mg/m² once every 21 days

Route of admnistration


Defined daily dose

75 - 75 mg per m² of body surface area (BSA)

Dosage regimen

From 75 To 75 mg per m² of body surface area (BSA) once every 21 day(s)

Detailed description

In chemotherapy naive patients treated for non-small cell lung cancer, the recommended dose regimen is docetaxel 75 mg/m² immediately followed by cisplatin 75 mg/m² over 30-60 minutes. For treatment after failure of prior platinum-based chemotherapy, the recommended dose is 75 mg/m² as a single agent.

In combination with cisplatin

For patients who are dosed initially at docetaxel 75 mg/m² in combination with cisplatin and whose nadir of platelet count during the previous course of therapy is <25,000 cells/mm³, or in patients who experience febrile neutropenia, or in patients with serious non-haematologic toxicities, the docetaxel dose in subsequent cycles should be reduced to 65 mg/m².

Dosage considerations

Docetaxel is administered as a one-hour infusion every three weeks.

Active ingredient


Docetaxel is an antineoplastic agent which acts by promoting the assembly of tubulin into stable microtubules and inhibits their disassembly which leads to a marked decrease of free tubulin.

Read more about Docetaxel

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