Ulcers following NSAID therapy or associated with continued NSAIDs

Active Ingredient: Ranitidine

Indication for Ranitidine

Population group: only adults (18 years old or older)

For this indication, competent medicine agencies globally authorize below treatments:

300 mg in 2 divided doses daily

Route of admnistration

Oral

Defined daily dose

300 - 300 mg

Dosage regimen

From 150 To 150 mg 2 time(s) per day every day

Detailed description

150 mg twice daily may be given concomitantly with NSAID therapy.

In duodenal ulcer, 300 mg twice daily for 4 weeks results in healing rates which are higher than those at 4 weeks with ranitidine 150 mg twice daily or 300 mg at night. The increased dose has not been associated with an increased incidence of unwanted effects.

8 weeks treatment may be necessary for ulcers following NSAID therapy.

Active ingredient

Ranitidine

Ranitidine is a specific rapidly acting histamine H2-antagonist. It inhibits basal and stimulated secretion of gastric acid, reducing both the volume and the acid and pepsin content of the secretion. Ranitidine has a relatively long duration of action and so a single 150 mg dose effectively suppresses gastric acid secretion for twelve hours.

Read more about Ranitidine

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