Mild-to-moderate COVID-19

Active Ingredient: Bamlanivimab

Indication for Bamlanivimab

Population group: only adolescents (12 years - 18 years old)

Treatment of mild-to-moderate COVID-19 in patients aged ≥12 years who weigh ≥40 kg with positive results of direct SARS-CoV-2 viral testing, and who are at high risk for progressing to severe COVID-19 and/or hospitalization.

Patient selection

High-risk defined as meeting at least 1 of these criteria:
Chronic kidney disease
Immunosuppressive disease
Receiving immunosuppressive treatment

Additional high-risk factors in patients aged 12-17 years:
BMI ≥85th percentile for their age and sex based on CDC growth charts
Sickle cell disease
Congenital or acquired heart disease
Neurodevelopmental disorders (eg, cerebral palsy)
Medical-related technological dependence (eg, tracheostomy, gastrostomy, positive-pressure ventilation [not related to COVID-19])
Asthma, reactive airway diease, or other chronic respiratory disease requiring daily medication for control

For this indication, competent medicine agencies globally authorize below treatments:

700 mg once

Route of admnistration


Defined daily dose

700 - 700 mg

Dosage regimen

From 700 To 700 mg once every day

Detailed description

700 mg as a single IV infusion over 60 minutes

Administer as soon as possible after positive viral test for SARS-CoV-2 and within 10 days of symptom onset in patients at high-risk for progressing to severe COVID-19 and/or hospitalization.

Dosage considerations

Single IV infusion over 60 minutes.

Active ingredient


Bamlanivimab is a recombinant, neutralizing human IgG1 monoclonal antibody (mAb) directed against the spike protein of SARS-CoV-2. It is designed to block viral attachment and entry into human cells, thus neutralizing the virus, potentially treating COVID-19.

Read more about Bamlanivimab

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