Glucagon is indicated for treatment of severe hypoglycaemic reactions, which may occur in the management of insulin treated children and adults with diabetes mellitus.
For this indication, competent medicine agencies globally authorize below treatments:
For: Children Adolescents
Subcutaneous
0.5 - 1 mg per kg of body weight
From 0.5 To 1 mg per kg of body weight once every day
Administer 0.5 mg (children below 25 kg or younger than 6–8 years) or 1 mg (children above 25 kg or older than 6–8 years).
The patient will normally respond within 10 minutes. When the patient has responded to the treatment, give oral carbohydrate to restore the liver glycogen and prevent relapse of hypoglycaemia. If the patient does not respond within 10 minutes, intravenous glucose should be given.
For: Children Adolescents
Intravenous
0.5 - 1 mg per kg of body weight
From 0.5 To 1 mg per kg of body weight once every day
Administer 0.5 mg (children below 25 kg or younger than 6–8 years) or 1 mg (children above 25 kg or older than 6–8 years).
Onset of action after an intravenous injection of 0.2–0.5 mg occurs within one minute and the duration of effect is between 5 and 20 minutes. The onset of action after an intramuscular injection of 1–2 mg occurs after 5–15 minutes and lasts approximately 10–40 minutes.
For: Adults (18-64) Elders (65+)
Intramuscular
1 mg
1 mg once every day
Administer 1 mg by intramuscular injection.
The patient will normally respond within 10 minutes. When the patient has responded to the treatment, give oral carbohydrate to restore the liver glycogen and prevent relapse of hypoglycaemia. If the patient does not respond within 10 minutes, intravenous glucose should be given.
For: Adults (18-64) Elders (65+)
Subcutaneous
1 mg
1 mg once every day
Administer 1 mg by subcutaneous injection.
The patient will normally respond within 10 minutes. When the patient has responded to the treatment, give oral carbohydrate to restore the liver glycogen and prevent relapse of hypoglycaemia. If the patient does not respond within 10 minutes, intravenous glucose should be given.
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