HIV-1 infection

Active Ingredient: Etravirine

Indication for Etravirine

Population group: only adults (18 - 65 years old)

Etravirine, in combination with a boosted protease inhibitor and other antiretroviral medicinal products, is indicated for the treatment of human immunodeficiency virus type 1 (HIV-1) infection in antiretroviral treatment-experienced adult patients.

For this indication, competent medicine agencies globally authorize below treatments:

400 mg in 2 divided doses daily

Route of admnistration


Defined daily dose

400 - 400 mg

Dosage regimen

From 200 To 200 mg 2 time(s) per day every day

Detailed description

The recommended dose of etravirine for adults is 200 mg taken orally twice daily following a meal.

Missed dose

If the patient misses a dose of etravirine within 6 hours of the time it is usually taken, the patient should take it following a meal as soon as possible and then take the next dose at the regularly scheduled time. If a patient misses a dose by more than 6 hours of the time it is usually taken, the patient should not take the missed dose and simply resume the usual dosing schedule.

If a patient vomits within 4 hours of taking the medicine, another dose of etravirine should be taken following a meal as soon as possible. If a patient vomits more than 4 hours after taking the medicine, the patient does not need to take another dose until the next regularly scheduled time.

Dosage considerations

Take after meal.

Active ingredient


Etravirine is an non-nucleoside reverse transcriptase inhibitors (NNRTI) of human immunodeficiency virus type 1 (HIV-1). Etravirine binds directly to reverse transcriptase (RT) and blocks the RNA-dependent and DNA-dependent DNA polymerase activities by causing a disruption of the enzyme’s catalytic site.

Read more about Etravirine

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