Active Ingredient: Propofol
Propofol is a short-acting intravenous general anaesthetic for sedation of ventilated patients over 16 years of age in the intensive care unit.
For this indication, competent medicine agencies globally authorize below treatments:
For:
In the case that patient age in years is > 16 :
Intravenous, between 0.3 milligrams propofol and 4 milligrams propofol, over the duration of 1 hour.
For sedation during intensive care it is advised that propofol should be administered by continuous infusion. The infusion rate should be determined by the desired depth of sedation. In most patients sufficient sedation can be obtained with a dosage of 0.3–4 mg/kg/h of propofol. Propofol is not indicated for sedation in intensive care of patients of 16 years of age or younger. Administration of propofol by Diprifusor TCI system is not advised for sedation in the intensive care unit.
Where propofol is used for maintenance of sedation the rate of infusion or 'target concentration' should also be reduced. Patients of ASA grades 3 and 4 will require further reductions in dose and dose rate. Rapid bolus administration (single or repeated) should not be used in older people as this may lead to cardiorespiratory depression.
Liability Disclaimer : RxReasoner has utilized reasonable care in providing content and services that are accurate, complete and up to date. However, RxReasoner does not accept any responsibility or liability about it. The content and services of RxReasoner are for informational purposes only and they are not intended to be a substitute for the knowledge, expertise, skill, and judgment of physicians, pharmacists, nurses, or other healthcare professionals involved in patient care. RxReasoner offers no medical advice. Users are responsible for the use of the provided content. A shown indication or treatment should not be construed to indicate that the medication is safe, appropriate, or effective in any given patient or under any particular circumstances. The absence of an indication or treatment should not roule out the existence of other appropriate medications. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition or medicament. RxReasoner is not liable for any damages allegedly sustained arising out of the use of its content and services.