Generalised anxiety disorder

Active Ingredient: Pregabalin

Indication for Pregabalin

Population group: only adults (18 years old or older)

Pregabalin is indicated for the treatment of Generalised Anxiety Disorder (GAD) in adults.

For this indication, competent medicine agencies globally authorize below treatments:

150-600 mg in 2 divided doses daily

Route of admnistration

Oral

Defined daily dose

150 - 600 mg

Dosage regimen

From 75 To 300 mg 2 time(s) per day every day

Loading dose

150 mg

Detailed description

The dose range is 150 to 600 mg per day given as two or three divided doses. The need for treatment should be reassessed regularly. Pregabalin treatment can be started with a dose of 150 mg per day. Based on individual patient response and tolerability, the dose may be increased to 300 mg per day after 1 week. Following an additional week the dose may be increased to 450 mg per day. The maximum dose of 600 mg per day may be achieved after an additional week.

Discontinuation of pregabalin

In accordance with current clinical practice, if pregabalin has to be discontinued, it is recommended this should be done gradually over a minimum of 1 week independent of the indication.

Dosage considerations

It may be taken with or without food.

150-600 mg in 3 divided doses daily

Route of admnistration

Oral

Defined daily dose

150 - 600 mg

Dosage regimen

From 50 To 200 mg 3 time(s) per day every day

Loading dose

150 mg

Detailed description

The dose range is 150 to 600 mg per day given as two or three divided doses. The need for treatment should be reassessed regularly. Pregabalin treatment can be started with a dose of 150 mg per day. Based on individual patient response and tolerability, the dose may be increased to 300 mg per day after 1 week. Following an additional week the dose may be increased to 450 mg per day. The maximum dose of 600 mg per day may be achieved after an additional week.

Discontinuation of pregabalin

In accordance with current clinical practice, if pregabalin has to be discontinued, it is recommended this should be done gradually over a minimum of 1 week independent of the indication.

Dosage considerations

It may be taken with or without food.

Active ingredient

Pregabalin

Pregabalin binds to an auxiliary subunit (α2-δ protein) of voltage-gated calcium channels in the central nervous system.

Read more about Pregabalin

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