Volume deficiency

Active Ingredient: Albumin

Indication for Albumin

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

Restoration and maintenance of circulating blood volume where volume deficiency has been demonstrated, and use of a colloid is appropriate.

The choice of albumin rather than artificial colloid will depend on the clinical situation of the individual patient, based on official recommendations.

For this indication, competent medicine agencies globally authorize below treatments:

Individual dosing

Route of admnistration

Intravenous

Defined daily dose

100 - 200 g

Dosage regimen

From 100 To 200 g once every day

Detailed description

The dose required depends on the size of the patient, the severity of trauma or illness and on continuing fluid and protein losses. Measures of adequacy of circulating volume and not plasma albumin levels should be used to determine the dose required.

If human albumin is to be administered, haemodynamic performance should be monitored regularly; this may include:

  • arterial blood pressure and pulse rate
  • central venous pressure
  • pulmonary artery wedge pressure
  • urine output
  • electrolyte
  • haematocrit/haemoglobin

Active ingredient

Albumin

Human albumin accounts quantitatively for more than half of the total protein in the plasma and represents about 10% of the protein synthesis activity of the liver. The most important physiological functions of albumin results from its contribution to oncotic pressure of the blood and transport function. Albumin stabilises circulating blood volume and is a carrier of hormones, enzymes, medicinal products and toxins.

Read more about Albumin

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