Post operative nausea and vomiting (PONV)

Active Ingredient: Ondansetron

Indication for Ondansetron

Population group: only minors (0 - 18 years old)

For this indication, competent medicine agencies globally authorize below treatments:

0.1 mg/kg once

Route of admnistration

Intravenous

Defined daily dose

0.1 mg per kg of body weight

Dosage regimen

0.1 mg per kg of body weight once every day

Detailed description

For prevention of PONV in paediatric patients having surgery performed under general anaesthesia, a single dose of ondansetron may be administered by slow intravenous injection (not less than 30 seconds) at a dose 0.1 mg/Kg up to a maximum of 4 mg either prior to, at or after induction of anaesthesia.

For the treatment of PONV after surgery in paediatric patients having surgery performed under general anaesthesia, a single dose of ondansetron may be administered by slow intravenous injection (not less than 30 seconds) at a dose of 0.1mg/kg up to a maximum of 4mg.

There are no data on the use of ondansetron in the treatment of PONV children below 2 years of age.

Active ingredient

Ondansetron

Ondansetron is a potent, highly selective 5HT3 receptor-antagonist. Its precise mode of action in the control of nausea and vomiting is not known.

Read more about Ondansetron

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