Gastro-oesophageal reflux disease

Active Ingredient: Pantoprazole

Indication for Pantoprazole

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Symptomatic gastro-oesophageal reflux disease.

For this indication, competent medicine agencies globally authorize below treatments:

40 mg once daily

Route of admnistration


Defined daily dose

40 - 40 mg

Dosage regimen

From 40 To 40 mg once every day for 60 day(s)

Detailed description

The recommended intravenous dose is 40 mg pantoprazole per day.

Dosage considerations

A ready-to-use solution is prepared in 10 ml of sodium chloride 9 mg/ml (0.9%) solution for injection. The prepared solution may be administered directly or may be administered after mixing it with 100 ml sodium chloride 9 mg/ml (0.9%) solution for injection or glucose 55 mg/ml (5%) solution for injection.

The medicinal product should be administered intravenously over 2-15 minutes.

20 mg once daily

Route of admnistration


Defined daily dose

20 - 20 mg

Dosage regimen

From 20 To 20 mg once every day for 56 day(s)

Detailed description

The recommended oral dose is 20 mg per day. Symptom relief is generally accomplished within 2-4 weeks. If this is not sufficient, symptom relief will normally be achieved within a further 4 weeks.

When symptom relief has been achieved, reoccurring symptoms can be controlled using an on-demand regimen of 20 mg once daily, twhen required. A switch to continuous therapy may be considered in case satisfactory symptom control cannot be maintained with on-demand treatment.

Dosage considerations

It should be swallowed 1 hour before a meal with some water.

Active ingredient


Pantoprazole is a substituted benzimidazole which inhibits the secretion of hydrochloric acid in the stomach by specific blockade of the proton pumps of the parietal cells.

Read more about Pantoprazole

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