Acute lymphoblastic leukaemia (ALL)

Indication for Idarubicin

Population group: Suitable for both men and women, only adults (18 years old or older)

For second line treatment of relapsed acute lymphoblastic leukaemia (ALL).

For this indication, competent medicine agencies globally authorize below treatments:

12 mg/m² once daily for 3 days

Route of admnistration

Intravenous

Defined daily dose

12 - 12 mg per m² of body surface area (BSA)

Dosage regimen

From 12 To 12 mg per m² of body surface area (BSA) once every day for 3 day(s)

Detailed description

As single agent in ALL the suggested dose in adults is 12 mg/m² i.v. daily for 3 days.

Active ingredient

Idarubicin is a DNA intercalating anthracycline which interacts with the enzyme topoisomerase II and has an inhibitory effect on nucleic acid synthesis. Idarubicin has been shown to have a higher potency with respect to daunorubicin and to be an effective agent against murine leukaemia and lymphomas both by i.v. and oral routes.

Read more about Idarubicin

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